The Museum of Cultural History of Latgale, Kedainiai Regional Museum, M. Bogdanovich Grodno museum have accumulated a rich local cultural and historical heritage of the region. However, it is necessary to attribute a cross-border significance and availability to this heritage since these regions are united by a common history (the period of the Great Duchy of Lithuania in the 12th–15th centuries, Rzeczpospolita in the 16th–18th c., Vitebsk Guberniya in the 16th–20th c.) and similar manifestations of traditional culture. Nowadays when the newest technologies make their appearance both in everyday life and in the environment of museums, education and research, new possibilities open up for new interactive offers for using of the accumulated heritage relating to the history of civilization and for popularizing it for various target audiences, in particular, for the younger generation. The creation of the virtual museum would allow: 1) to attract the younger generation for acquiring the heritage relating to the history of civilization by arousing interest in a museum as a modern and diverse institution, developing strong features of the regional identity; 2) to update operatively and to change virtually the available information in the permanent exhibitions, 3) to make available the common heritage relating to the history of Grodno, Rēzekne, Kedainiai by applying an innovative point of view: showing a concept (a cultural object).