PORT-5R addresses the issues related to the management of port activities located in highly populated areas and/or near areas of naturalistic interest. The project aims at the sustainable management of ship-generated waste in cooperation area ports by adopting the following five-pronged strategy: Reduction, Reuse, Recycling, Collection and Recovery. PORT-5R sets forth the following outcomes: 1. Guidelines for the preparation of a joint plan to prevent, reduce and dispose of marine waste in ports. The Plan considers the different ways of recovering waste from ships according to waste type (bilge water, urban-like waste, kitchen waste, etc.), the problems connected to the transfer of waste to the plants and the capacity of these facilities to handle the amount of waste collected and therefore the number of ships calling at the port; 2. The creation of a joint planning platform (for the networking of good practices and experts in the sector); 3. The development of specific wastewater and solid waste pilot actions, focusing on improving water quality for the former and traceability for the latter, by using tags/transponders (fixed and mobile identification, exact data collected automatically for calculating the precise tariff, stimulation of virtuous user behaviour and speedy collection). The project develops innovative aspects such as the use of ICT technologies for port waste information management, including hydrodynamic systems and high-pressure canal-jets for pipeline reclamation. The cross-border approach is necessary for the definition of common strategies of integrated waste management by macro port areas sharing plants and knowledge.