Agriculture and livestock are key sectors in the MED area. Regions involved in the project are characterized by intensive cattle and pig livestock farming, producing large amounts of waste that represent a major source of pollution, an environmental challenge for society and an economic problem for farms. There is a great unexploited potential for MED regions to spread the use of innovative technologies that convert livestock waste into resource. RE-LIVE WASTE tests innovative solutions for livestock waste management in selected MED regions, taking into account technical, environmental, economic and legal aspects. Project pilot actions will transform livestock waste into organic high-value commercial fertilizers (as Struvite), contributing to smart and sustainable growth and to the creation of new business and market opportunities. Project outputs include 4 demonstrative Struvite Precipitation (SP) plants, and policy guidelines to stimulate innovation adoption and to set-up a common suitable legal framework. The transnational network creation aims at sharing innovative technologies able to reduce ecological footprint of livestock sector. Involvement of actors of quadruple helix and a beneficiaries-oriented approach will ensure a concrete impact on the involved territories and transferability of results to other EU regions.