Historical cultural landscapes are typical of most parts of Central Europe. However, nowadays the diversity of these cultural landscapes is endangered by neglected nature protection and heritage preservation and by depopulation processes. The CULTURAL LANDSCAPE project aims at protecting and managing landscapes as a cornerstone of the CADSES identity and as a source of sustainable regional development. Based on a cross-sector approach covering nature protection, heritage preservation and rural development, and supported by a transnational research framework, the project develops best-practice examples for the implementation of the European Landscape Convention. This includes raising the awareness of cultural landscapes by transnational surveys (“digital land register“) and an open-access web portal, “Landscape Wikipedia”, to integrate landscapes into regional development by exemplary pilot projects in the fields of agriculture, tourism, regional marketing, and renewable energies. Moreover, it aims at elaborating integrated strategies for the protection and development of cultural landscapes at regional, national and CADSES level. The project primarily intends to establish a transnational network to help to enact the European Landscape Convention in the CADSES area. In close contact with the Spatial Planning and Landscape Division of the Council of Europe, the network will be open to further partners.