The main objective of the 3D4MED project is to develop an innovative 3D matrix for tissue engineering with the goal of reconstructing, regenerating, or replacing the tissue of defective organs. These matrices are a growth medium developed from biocompatible polymers with shape memory properties. The originality of this project lies, on the one hand, in the formulation of new biocompatible polymers and, on the other hand, in the preparation of ready-to-use implants with complex and individualised architectures using an additive manufacturing process. These implants are made of functional and biocompatible GMP grade polymers with shape memory properties, minimising mechanical trauma during and after implantation, while promoting cell recolonisation and tissue integration. The project aims to meet several challenges: a scientific and technical challenge to produce an innovative product; the second is the further development of the tissue-engineered product, starting from the concept up to the production of an operational prototype validated in preoperative condition; a key step when it comes to promoting the product among companies. These challenges are being met within a consortium comprised of the various complementary areas of expertise found within the cross-border area.