The Industrial revolution n4is on progress: Schools, Universities and SMEs are fully involved to provide necessary skills and innovation processes. The Alpine Area is involved and several local and EU actions are addressing this challenging topic. The transboarder area interested by E-EDU4.0 is on this topic with assistance and services provided by local intermediaries to SMEs, but needs additional efforts to provide necessary skills both for the educational programmes for Schools and Universities and the training actions addressed to SMEs. E-EDU4.0aims to support the Industry 4.0 process strengthening the impact of training and educational programmes with a much more effective transboarder cooperation and a better synergy concerning training and educational programmes from one side, laboratories and didactic infrastructures from the other. The project builds necessary networks of actors dealing with skills and learning programmes, organize their activities and provide necessary tools and necessary equipment to complete the instruments and the infrastructures available for the learning process both at local and transnational level. The concrete testing of the qualification programmes with local and transboarder actions addressed to SMEs and students will improve the project impact and open to new synergies and transferring actions. An overall platform with materials and mapping will support the networking, the cooperation and the durability of the project actions undertaken.