Dynamic territorial development depends on an optimal combination of access to services and resources. Good accessibility and connectivity is one of the most crucial factors in deciding on a location for economic activities. This leads to the fact that fast, relatively cheap, reliable but also sustainable freight and passenger transport, has become one of the essential prerequisites for the competitiveness of regions and regional economic development. This is why transport infrastructure developments and transport networks connecting Europe and its particular regions play such an important role in formulating the European policies as the Green Paper on Territorial Cohesion. This project shall strive for a comprehensive and integrated research approach, taking into account social, cultural, environmental, and economic aspects. Its aim is to deliver innovative results which can support the policy development in the field of transport and accessibility improvement, territorial development, competitiveness and cohesion. It shall support policy makers in finding trade-offs between promoting accessibility for passenger and freight transport and competitiveness, sustainability, saving energy and territorial development.