Recently cultural tourism has become a promising economic factor and a growing sector of the tourism industry. Destinations with a cultural tourism potential might profit from enhancing the tourism infrastructure in various ways: Cultural tourism contributes to shaping regional identities, it strengthens local economies and it has a positive influence on employment opportunities. All partner regions of the CHIRON project from Greece, Hungary, Slovakia, Poland, Germany, Bulgaria and Ukraine have a rich cultural heritage and a cultural tourism potential which need further development, promotion and marketing. Moreover, the institutions and infrastructure of the project areas need enhancement to facilitate cultural tourism. Here in particular transnational co-operation and networking which mobilises, links and co-ordinates relevant stakeholders would be helpful.