The border area between Germany, Czech Republic, and Poland is characterised by a low level of transnational cooperation between science and industry. Thus, the most important aim of TRANS³net is to shape conditions for building up a well working innovation system in this tri-national region. This objective is realised by establishing strong ties and a self-sustaining cooperation between ‘transfer promotors’ and further actors of the scientific, economic and public sphere. By involving all key players relevant for knowledge and technology transfer, the project provides a solution to overcome the multifaceted obstacles concerning transnational cooperation between science and industry. This contributes on one hand to the success of single economic and research entities, thus, to the economic and social prosperity in the defined area and, in consequence to the improvement of quality of life there. On the other hand, project provides a solution which is transferable to other regions and could indeed improve the innovation capacity in whole Central Europe. Thereby, the establishment of a common understanding of the transfer process (reference model) as well as an analysis of the current transfer situation will be the decisive basis to provide the targeted transparency of national structures, legal arrangements, and innovation-relevant players. The formation of trustful linkages between those players will be promoted through piloting various low-threshold event formats. A catalogue with manuals of such transferable pilot actions is provided. Besides a strategy as working basis for a transnational network, a cooperation network model to ensure its continuation is developed. Finally, we intend to create an agreement between network members as basis for sustainability. The project objectives can only be achieved at transnational level. Partners act as regional experts and as supporters of the transnational networking in their respective regions.