The SEEDS partnership aims to build and test a coherent framework for planning and implementing joint sustainable internationalisation strategies and actions for small- and medium-sized enterprises (SMEs) in CADSES, which will enable the effective support of relevant actions. The SME internationalisation process needs to be considered as a part of the general spatial development strategies to serve the implementation of the European Spatial Development Perspective (ESDP). This is essential for achieving sustainable, harmonised and balanced development in Central and South-Eastern Europe. In general the project creates a basis for effective SME internationalisation, in a way that will promote balanced and harmonised spatial development mainly by networking and supporting of the SMEs.